Potential drug candidate for AP-4 HSPs identified
AP-4 blood biomarker discovered also
Welcome to the HSP Research Foundation – created in 2005 to find an effective treatment for the Hereditary Spastic Paraplegias (HSPs) – a group of progressive, inherited, degenerative diseases affecting mainly the legs, causing spasticity, muscle weakness and severely impairing walking.
The HSP Research Foundation is an incorporated, registered Australian charity that facilitates and funds research to find effective treatments and cures. The Foundation is also the community hub for people with HSP in Australia, creating awareness and providing information, education and support. Read more »
Spring Edition 2023
A new website is under development
AP-4 blood biomarker discovered also
Peripheral nerve involvement in SPG4 & SPG7
Approved statins may help fix the problem
Marker of disease severity / treatment effectiveness
Single lower-back wearable inertial sensor used
Gene testing helps with diagnosis
Protein regulates structural plasticity of neurons
Other genes & epigenetics play a part
Research from Taiwan, Spain, China, France, USA, South Korea, Italy, Turkiye, India and Brazil
Phase 1 study in humans
14 commentsExpansion of SPG50 clinical trials
Another project with community member Jason
Improve walking, help prevent falls
1 commentHSP community member writes a book
Even for those in wheelchairs
An individual reflection
2 comments2023 ‘Queensland Greats’ award
1 commentLatest research presentations
Get-togethers in NSW, Vic, ACT, WA & Qld
Big changes coming
1 commentNew regulations a step in right direction
US Government enforcement improving compliance