Impaired mitochondria cause SPGs 11 & 48
Specific impairments identified
HSP Research Foundation
Welcome to the HSP Research Foundation – created in 2005 to find an effective treatment for the Hereditary Spastic Paraplegias (HSPs) – a group of progressive, inherited, degenerative diseases affecting mainly the legs, causing spasticity, muscle weakness and severely impairing walking.
The HSP Research Foundation is an incorporated, registered Australian charity that facilitates and funds research to find effective treatments and cures. The Foundation is also the community hub for people with HSP in Australia, creating awareness and providing information, education and support. Read more »
Autumn Edition 2022
Winter edition to be published early June 2022
Research highlights »
New crossbred SPG4 mouse holds great promise
Aim to use for testing SPG4 therapies
13 commentsSpecial imaging yields SPG4 insights
Axonal damage measured
Shortening the “diagnostic odyssey”
Whole genome sequencing the key
HSPs studied in children
20 new genetic variants discovered
Regulation of Spastin stability
Important for microtubules and nerve growth
New HSP genotypes and phenotypes
Research from Belgium, France, USA, Germany, Turkey, Serbia, Spain, Italy, China, Poland, Netherlands, Japan, Cyprus, Finland, Austria, Lebanon, Chile, Morocco
Living with HSPmanagement & treatment news »
Disclosing diagnosis to loved ones
How, when, where is best?
Intra-thecal Baclofen (ITB) in HSP children
Treatment success in managing spasticity
HSPer in Aust. Wheelchair League squad
World Cup beckons later this year
HSP Webinar Series 2022
Neuro Physio Role in HSP Management
2 commentsNew system for air travel with wheelchairs
Similar to systems used in vehicles
IVF in SPG3A HSP
Normal pregnancy achieved
Professional wheelchair basketball in the UK
Teenager with HSP signed to play
Epilepsy & cognitive impairment in SPG4
Seizures successfully treated
HSP in a Neurogenetics outpatient clinic
Facts and figures
Foundation News »
Dylan Alcott Australian of the Year 2022
His inspiration yielding results
28 February is Rare Disease Day
Show your support
NDIS funding cuts
Tens of thousands affected
Groundbreaking UN Resolution on Rare Diseases
Adopted by all 193 Member States
New Foundation collaboration
Genetic Cures for Kids
US HSP support group
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