Huge study of SPG4 in Italy
Important data and findings generated
HSP Research Foundation
Welcome to the HSP Research Foundation – created in 2005 to find an effective treatment for the Hereditary Spastic Paraplegias (HSPs) – a group of progressive, inherited, degenerative diseases affecting mainly the legs, causing spasticity, muscle weakness and severely impairing walking.
The HSP Research Foundation is an incorporated, registered Australian charity that facilitates and funds research to find effective treatments and cures. The Foundation is also the community hub for people with HSP in Australia, creating awareness and providing information, education and support. Read more »
Winter Edition 2022
Spring edition to be published early September 2022
Research highlights »
How SPG4 first shows up
Potential biomarker for treatment response
Another potential mechanism in SPG4
Toxic effect rather than shortage in some cases
New HSP mouse for testing potential therapies
Mouse exhibits a range of HSP characteristics
Disease-causing mechanism of SPG15 explored
Links between lysosomes, lipids & nerve function
A new explanation for AP-4 deficiency syndrome
Reduced levels of a key enzyme affect neurite growth
Lipid imbalance in SPG61 described
Potential therapeutic pathway identified
Role of Spastin & cognitive dysfunction in HSP
Understanding of AMPAR receptor advanced
Genetic analysis reveals HSP complexity
47 new HSP variants identified
New HSP genotypes and phenotypes
Research from China, Spain, USA, Canada, Czech Republic, Russia, Norway, South Korea, Slovenia
Living with HSPmanagement & treatment news »
Upcoming webinar, 20 June
Exploring home & living solutions, having independence
COVID pandemic still with us
What you need to know
For parents of children with HSP
Take a Survey to help research
HSP orthotic wins student design prize
Victorian HSP family the motivation
9th Annual Survey of HSPers globally
Data on wellbeing, relationships, acceptance
Childhood-onset HSP cases reviewed
8 years from symptoms to genetic diagnosis
Trunk movement and balance in HSP
How they are related and why
Genetic testing diagnostic rate improved
Full clinical picture & revisiting test results important
Foundation News »
Research program update June 2022
Finding a pathway forward
3 comments2 Fundraisers for HSP research
An ‘open garden’ & a wedding
Families of SPG56 children meet
Research underway to find a cure
Riley Moore, swimmer who has HSP
5 gold medals at Australian Para Swim Titles
Gene therapy for the HSPs
What’s the current status?
2 commentsRare Care Centre in WA
For children with rare & undiagnosed conditions
Models with disability at Australian Fashion Week
And a model with HSP for Victoria’s Secret
Where to for the NDIS?
Many hoping for a better future
Newsletters from HSP groups UK & France
See what’s happening in other groups
