Research team members presenting
Research team members Gautam Wali and Kishore Kumar were both invited presenters to recent well-regarded symposiums held respectively by the European TreatHSP consortium https://www.treathsp.net/ and the Tom Wahlig Foundation https://www.hsp-info.de/ in Germany.
Presentations were made by researchers from Germany, Belgium, France, Spain, Italy, Austria, Canada, Australia and the USA about their work on the HSP.
Gautam was invited to speak about his current work and future plans for HSP biomarker development, while Kishore addressed the challenges and controversies facing HSP genetics in his presentation.
The review process for the clinical trial program continues, with the circumstances presented by the COVID-19 pandemic ongoing globally.
Meanwhile, important progress continues to be made in biomarker development with an expanded program covering more applications (diagnosis; disease severity; clinical trials; disease onset) and more HSP types. This is in the conceptual stage with plans expected to be drafted in the first quarter of 2022.
Alan Mackay-Sim and Gautam Wali are also currently writing a scientific research paper on the biomarker findings in SPG4.
The SPG7 research program moves forward with the long and labour-intensive process of induced pluripotent stem cell differentiation well underway. The desired end point of this phase is the production of cell cultures with predominantly induced SPG7 neurons that will provide the basis for further experimentation.