Comparing HSP with Spastic Diplegia

A study of children with HSP and Spastic Diplegia (SD) shows different gait patterns for each condition, particularly at the knee joint and in the thigh muscle.


The predominant clinical feature of patients with Hereditary Spastic Paraparesis (HSP) is gait disturbance owing to spasticity and weakness of the lower limbs; the spasticity in early-onset disease (infancy or childhood) often cannot be distinguished from mild form of spastic diplegia (SD).


The aim of this study was to quantify the gait strategy in HSP and SD children, focusing on the differences between groups as concerns functional limitation during gait. 9 HSP and 16 SD children were evaluated using Gait Analysis; kinematic and kinetic parameters and EMG pattern during walking were identified and calculated to compare the two gait strategies.


The results revealed that these two pathologies are characterised by different gait strategies. In particular we found that knee joint, in terms of kinematics and kinetics, and rectus femoris pattern represent discriminatory aspects in order to compare and differentiate gait patterns of HSP and SD children.


The findings strongly support the issue that HSP and SD patients need individualised therapeutical program, either neurosurgical or pharmacological treatment, based on the quantification of gait deficiencies and in order to address the peculiarity of their motor limitations and to prevent the onset of compensatory strategies.


SOURCE: Eur J Paediatr Neurol. 2011 Mar;15(2):138-45. Epub 2010 Sep 15.  Copyright © 2010 European Paediatric Neurology Society. Published by Elsevier Ltd. All rights reserved.  PMID: 20829081


3D gait analysis in patients with hereditary spastic paraparesis and spastic diplegia: a kinematic, kinetic and EMG comparison.


Piccinini L, Cimolin V, D’Angelo MG, Turconi AC, Crivellini M, Galli M.


IRCCS “E. Medea”, “La Nostra Famiglia” Association, Bosisio Parini, Lecco, Italy.


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