Research Highlights
Biomarker discovery for SPG5 HSP
Posted - February 2018 in Research Highlights
Two cholesterol derivatives identified
DDHD1 and DDHD2 HSP genes investigated
Posted - in Research Highlights
Lipid metabolism dysfunction the common cause
Adaptor Protein (AP) genes linked with 5 types of HSP
Posted - in Research Highlights
Mechanisms & processes described in 3 research studies
Rare form of SPG4 HSP misdiagnosed
Posted - in Research Highlights
Early-onset symptoms “misleading”
New HSP mutation found in FA2H gene
Posted - in Research Highlights
Early-onset and rapid progression SPG35 HSP
Promising treatment found for SPG5 HSP
Posted - December 2017 in Research Highlights
Atorvastatin reduces toxic fatty compounds in the brain
Next Generation gene testing telling a story
Posted - in Research Highlights
Much of HSP genetics still not understood
HSP differences in identical twins
Posted - in Research Highlights
More than genetic inheritance at play
Brain activity levels potential diagnostic for SPG4 HSP
Posted - in Research Highlights
Differences with disease severity identified
SPG2 HSP mechanism described
Posted - in Research Highlights
Loss of specialised support cells the cause
New HSP genotypes and phenotypes
Posted - in Research Highlights
From China, Japan, Italy, Brazil, UK, Korea, USA, Israel, Iran, Moldova, Greece, France, Belgium, Germany, UAE, Russia
Lower motor neurons impaired in some HSPs
Posted - in Research Highlights
Classification based on motor neuron involvement
Hereditary Ataxias and Spastic Paraplegias
Posted - in Research Highlights
Genes and symptoms overlap
HSP classification and terminology
Posted - in Research Highlights
Genetics explosion prompts update
New HSP genotypes and phenotypes
Posted - in Research Highlights
From Canada, USA, Pakistan, France, Japan, Czech Republic and Belgium
Questioning disease classification systems
Posted - June 2017 in Research Highlights
A mechanistically inspired classification proposed
Particular form of Spastin is toxic
Posted - in Research Highlights
Interferes with fast axonal transport
Axonal degeneration in HSP
Posted - in Research Highlights
Link between different classes of HSP proteins
