Research Highlights

Mitochondrial dysfunction in SPG31 HSP

Posted - February 2017 in Research Highlights

Function restored in cell samples

Two siblings with blood disorder and HSP

Posted - in Research Highlights

Both conditions autosomal recessive inheritance

Large national HSP database in Canada

Posted - in Research Highlights

Valuable resource for much-needed research

SPG42 HSP mechanism now well understood

Posted - in Research Highlights

Study of mice confirms earlier findings

Complicated form of HSP linked to new gene

Posted - in Research Highlights

Impaired lipid metabolism mechanism

SPG78 HSP mechanism investigated

Posted - in Research Highlights

Pathway leads to sell organelle impairment

New HSP genetic findings

Posted - in Research Highlights

From China, the Middle East, Italy and France

Severe pain and HSP

Posted - December 2016 in Research Highlights

Different types found

New HSP mechanism discovered

Posted - in Research Highlights

Potassium ion channel dysfunction

The role of proteins in axon regeneration

Posted - in Research Highlights

Spastin and Atlastin mechanism investigated

HSP cell abnormalities

Posted - in Research Highlights

Lipid droplet metabolism important

SPG57 HSP new findings

Posted - in Research Highlights

Mitochondrial impairment the cause

SPG48 HSP studied in depth

Posted - in Research Highlights

Multiple associated complications

New HSP genetic findings

Posted - in Research Highlights

From Hungary, Sudan, Australia and China

Australian success with whole genome sequencing

Posted - September 2016 in Research Highlights

Higher detection rates for HSP mutations

Recessive SPG35 HSP inherited from just one parent

Posted - in Research Highlights

Major implications for genetic counselling

Large Czech study of SPAST HSP

Posted - in Research Highlights

327 HSPers from 263 families gene tested

FARS2 gene mutation described

Posted - in Research Highlights

Causes recessive but pure SPG77 HSP

HSPer also found to have MS

Posted - in Research Highlights

First description of dual occurrence

Pure HSP study of children in Greece

Posted - in Research Highlights

Clinical and genetic findings