Research Highlights
Advances in understanding of the HSPs
Posted - September 2019 in Research Highlights
Insight into impaired functions and underlying mechanisms
Three rapid tests of HSP features developed
Posted - in Research Highlights
Potential drug target for SPG4 identified
New explanation for SPG4 causal mechanism
Posted - in Research Highlights
Both too little & too much Spastin to blame
Mitochondrial dynamics and HSP axon defects
Posted - in Research Highlights
Corrected by having less of key protein DRP1
SPG35 HSP overlaps FAHN & leukodystrophy
Posted - in Research Highlights
Phenotype, disease course, clinical & imaging biomarkers
New, dominant form of HSP, SPG80, described
Posted - in Research Highlights
Found in 10 geographically diverse families worldwide
Atlastin’s role in SPG3A explored
Posted - in Research Highlights
Mechanism and dynamics of impairment described
New HSP genotypes and phenotypes
Posted - in Research Highlights
Research from the UK, China, Pakistan, Italy, Spain, France, Turkey, Austria, Canada, USA & Germany
Large study of SPG7 HSP
Posted - June 2019 in Research Highlights
Genotype-phenotype correlations described
New brain imaging technology delivers
Posted - in Research Highlights
Brain Stem Atlas identifies SPG7 changes
POLR3A gene related syndromes include HSP
Posted - in Research Highlights
Large Norwegian study confirms earlier research
New HSP genotypes and phenotypes
Posted - in Research Highlights
Research from Iran, USA, Italy, Germany, Spain, Bulgaria, Canada, Austria, Saudi Arabia, China, Ireland and Finland
30-40% genetic diagnosis gap in HSPs
Posted - in Research Highlights
Need to look elsewhere for full picture of HSP genetics
Neurons more complex than thought
Posted - in Research Highlights
Prompts new view of how they function
Conventional view of SPG4 cause challenged
Posted - in Research Highlights
Additional mechanism suggested
New genetic type of HSP discovered
Posted - in Research Highlights
Associated with joint deformities in the feet and hands
