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Research Highlights

SPG15 HSP disease mechanism defined

Drug candidates for treatment identified

Vast differences in SPG4 HSP explained

Disruption to another gene SARS2 identified

Predicting disease onset in SPG4 HSP

Particular features of gait identified

Promising gene therapy developed

Effective for DNM2 related diseases including SPG

Detailed study of SPG15 HSP

Comprehensive characterisation established

Calcium balance disrupted in SPG4 HSP

Relevant to disease mechanism

Clinical gait analysis tells HSP from CP

Machine learning the key

RNA technologies for neurodegenerative diseases

Advantages and challenges

SPG87 mechanism findings

Lipid processing, ER & mitochondria involved

New HSP genotypes and phenotypes

Research from USA, Germany, Brazil, UK, China, Taiwan, Iran, Azerbaijan, Pakistan

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HSP Research Foundation

Welcome to the HSP Research Foundation - created in 2005 to find a cure for Hereditary Spastic Paraplegia - an inherited, degenerative disease affecting mainly the legs, causing muscle weakness, spasticity and severely impairing walking. Read more »

Information on this website and resources to which we have links are general knowledge about HSP. We are not medical professionals, nor do we offer medical advice. Always consult your own medical professionals regarding your particular circumstances.

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