Successfully tested in primates
Research Highlights
Neuroinflammation important in SPG11
Responsive to drug treatment in animal testing
Neuropsychology of SPG11 studied
Verbal fluency, memory & executive functions impaired
SPG3A & MS found in 9 cases
Positive response to immunotherapy for most
Recessive SPG87 both pure & complex forms
Mitochondria & endoplasmic reticulum impairments found
SPG56 mouse studies provide insight
Diagnostic biomarkers & possible treatments identified
SPG80 mice show HSP symptoms
Insight into how SPG80 is caused
New HSP genotypes and phenotypes
Research from USA, Germany, Turkey, China, India, France, Japan, Austria
Huge study of SPG4 in Italy
Important data and findings generated
How SPG4 first shows up
Potential biomarker for treatment response