Large study in China confirms previous findings
Research Highlights
New findings on SPG54 HSP
Mitochondria now implicated
New HSP genotypes and phenotypes
Research from China, Japan, Germany, Turkey and Australia
Mitochondrial impairment studied in SPG15 & 48 HSP
Function restored with treatment in lab experiments
SPG10 HSP gene now linked with Motor Neurone Disease
Previously linked to Charcot Marie Tooth
New HSP gene ACO2 discovered
Associated with recessive complicated HSP
Mechanism of AP-4 related HSPs investigated
AP-4 deficiency underlies four types of HSP
SPAST mutation affects adjacent gene
Combined effect causes complicated HSP
EPT1 mutation causes complicated HSP
Affects myelin sheath that covers nerves
Parkinsonism found in SPG7 HSP
Responsive to levodopa treatment