Research Highlights
Late-onset spastic paraplegia type 10 (SPG10)
Posted - May 2016 in Research Highlights
First-time discovered in an Asian family
REEP1 (SPG31) found with recessive inheritance
Posted - in Research Highlights
Previously associated only with dominant form
New HSP genetic findings
Posted - in Research Highlights
From Japan, Poland, England, China, Hungary, Morocco, Canada, Italy and the USA
Developing a ‘natural history’ of HSP
Posted - February 2016 in Research Highlights
Large German study lays the foundation
Atlastin (SPG 3A) investigated
Posted - in Research Highlights
Questions raised about regulation and role
SPG 8 HSP loss-of-function theory questioned
Posted - in Research Highlights
Implications for alternative gain-of-function hypothesis
Brain shrinkage found in SPG 2 HSP
Posted - in Research Highlights
Changes also in the myelin sheath around axons
Mechanism of complicated SPG49 HSP studied
Posted - in Research Highlights
TECPR2 protein deficiency affects multiple cell functions
New HSP genetics findings
Posted - in Research Highlights
From Germany, Norway, Pakistan, China, Japan
HSP research update December 2015
Posted - December 2015 in Research Highlights
Progress report from the research team
Protein interactions and nerve myelination
Posted - in Research Highlights
Helping understand more about SPG2 HSP
More overlap between HSP and CMT discovered
Posted - in Research Highlights
New gene for HSP implicated
New HSP genetics findings
Posted - in Research Highlights
From Japan, Greece, Belgium, Turkey, Italy, Canada
Promising results in HSP drug candidate class
Posted - September 2015 in Research Highlights
Nerve axon regeneration and improved motor function
What is now known about SPG4 HSP
Posted - in Research Highlights
More answers, but also more questions
Brain changes in SPG4 HSP measured
Posted - in Research Highlights
Correlated with disease duration and severity
76 HSP types from 59 genes … and counting
Posted - in Research Highlights
Gene testing advances show complex picture
How REEP1 mutations cause HSP clarified
Posted - in Research Highlights
Involved with both mitochondria and ER
