Research Highlights

SPG31/REEP1 study of cell function

Posted - June 2012 in Research Highlights

Abnormal mitochondrial organization and function

Spastin (SPG4) regulatory mechanisms studied

Posted - in Research Highlights

New targets found for mutation and drug screening

HSP and brain tissue damage

Posted - in Research Highlights

Found in both pure and complicated HSP

Measuring functional mobility in HSPers

Posted - in Research Highlights

Tools selected for Melbourne Gait Study

52 forms of HSP have now been found

Posted - in Research Highlights

Described by mode of inheritance

Spastin / Protrudin partnership studied

Posted - in Research Highlights

Role in normal neuron growth

SPG7 HSP discoveries

Posted - in Research Highlights

Wide spectrum of HSP forms

22 genes & 48 locations for HSP

Posted - March 2012 in Research Highlights

How many more to find?

New gene interacts with Spastin

Posted - in Research Highlights

Implicated in cell structural abnormalities

HSP and its ‘cousin’ CMT

Posted - in Research Highlights

Comparing genetics and cell function

Assessing nerve abnormalities in HSP

Posted - in Research Highlights

New measurement method tested

Large study of SPG31

Posted - in Research Highlights

Both pure & complex HSP found

Questions raised about Botox

Posted - December 2011 in Research Highlights

muscle loss and weakness with long term use

Large HSP survey in Japan

Posted - in Research Highlights

321 HSPers from 144 families registered

New HSP gene testing method

Posted - in Research Highlights

Sporadic HSP cases analysed

Link between reflexes and spasticity questioned

Posted - in Research Highlights

Over-active reflexes and calf muscle spasticity

KIF5 study relevant to SPG10 HSP

Posted - in Research Highlights

Neuronal transport mechanism identified

Dementia in some SPG4 HSPers

Posted - September 2011 in Research Highlights

Linked with Alzheimer’s gene

Rare HSP linked to Huntington’s disease

Posted - in Research Highlights

Both detected in one family over generations