Research Highlights

Stem Cell Research Project

Posted - September 2012 in Research Highlights

Progress Report September 2012

Mice with HSP used in study

Posted - in Research Highlights

Drugs reverse certain effects

SPG10 HSP and CMT type 2 strongly linked

Posted - in Research Highlights

Same gene mutation may cause both

Nerve abnormalities in HSP

Posted - in Research Highlights

Problems for some in the feet and legs

Nerve damage in SPG11 studied

Posted - in Research Highlights

Both white and grey matter damage found

HSP-impaired cell functions studied

Posted - June 2012 in Research Highlights

Importance of Reticulon protein demonstrated

SPG31/REEP1 study of cell function

Posted - in Research Highlights

Abnormal mitochondrial organization and function

Spastin (SPG4) regulatory mechanisms studied

Posted - in Research Highlights

New targets found for mutation and drug screening

HSP and brain tissue damage

Posted - in Research Highlights

Found in both pure and complicated HSP

Measuring functional mobility in HSPers

Posted - in Research Highlights

Tools selected for Melbourne Gait Study

52 forms of HSP have now been found

Posted - in Research Highlights

Described by mode of inheritance

Spastin / Protrudin partnership studied

Posted - in Research Highlights

Role in normal neuron growth

SPG7 HSP discoveries

Posted - in Research Highlights

Wide spectrum of HSP forms

22 genes & 48 locations for HSP

Posted - March 2012 in Research Highlights

How many more to find?

New gene interacts with Spastin

Posted - in Research Highlights

Implicated in cell structural abnormalities

HSP and its ‘cousin’ CMT

Posted - in Research Highlights

Comparing genetics and cell function

Assessing nerve abnormalities in HSP

Posted - in Research Highlights

New measurement method tested

Large study of SPG31

Posted - in Research Highlights

Both pure & complex HSP found

Questions raised about Botox

Posted - December 2011 in Research Highlights

muscle loss and weakness with long term use