Research Highlights

HSP types and patterns similar globally

Posted - September 2018 in Research Highlights

Large study in China confirms previous findings

New findings on SPG54 HSP

Posted - in Research Highlights

Mitochondria now implicated

New HSP genotypes and phenotypes

Posted - in Research Highlights

Research from China, Japan, Germany, Turkey and Australia

Mitochondrial impairment studied in SPG15 & 48 HSP

Posted - June 2018 in Research Highlights

Function restored with treatment in lab experiments

SPG10 HSP gene now linked with Motor Neurone Disease

Posted - in Research Highlights

Previously linked to Charcot Marie Tooth

New HSP gene ACO2 discovered

Posted - in Research Highlights

Associated with recessive complicated HSP

Mechanism of AP-4 related HSPs investigated

Posted - in Research Highlights

AP-4 deficiency underlies four types of HSP

SPAST mutation affects adjacent gene

Posted - in Research Highlights

Combined effect causes complicated HSP

EPT1 mutation causes complicated HSP

Posted - in Research Highlights

Affects myelin sheath that covers nerves

Parkinsonism found in SPG7 HSP

Posted - in Research Highlights

Responsive to levodopa treatment

Ataxia-spasticity spectrum disorders

Posted - in Research Highlights

Limitations in classification and diagnosis

New HSP genotypes and phenotypes

Posted - in Research Highlights

Research from France, Canada, Turkey, Germany, Norway, Spain, Italy, South Korea, India and the USA

Biomarker discovery for SPG5 HSP

Posted - February 2018 in Research Highlights

Two cholesterol derivatives identified

DDHD1 and DDHD2 HSP genes investigated

Posted - in Research Highlights

Lipid metabolism dysfunction the common cause

Adaptor Protein (AP) genes linked with 5 types of HSP

Posted - in Research Highlights

Mechanisms & processes described in 3 research studies

Rare form of SPG4 HSP misdiagnosed

Posted - in Research Highlights

Early-onset symptoms “misleading”

New HSP mutation found in FA2H gene

Posted - in Research Highlights

Early-onset and rapid progression SPG35 HSP

Promising treatment found for SPG5 HSP

Posted - December 2017 in Research Highlights

Atorvastatin reduces toxic fatty compounds in the brain

Next Generation gene testing telling a story

Posted - in Research Highlights

Much of HSP genetics still not understood

HSP differences in identical twins

Posted - in Research Highlights

More than genetic inheritance at play