Research Highlights
New HSP genotypes and phenotypes
Posted - May 2020 in Research Highlights
Research from Poland, Sudan, Spain, Iran, Korea, China, Czech Republic, Taiwan, Turkey, Mexico and Italy
Earlier HSP onset in successive generations
Posted - February 2020 in Research Highlights
Missense mutations also related to earlier onset
Potential treatment for SPG5 HSP identified
Posted - in Research Highlights
Promising results in mouse studies
New SPG4 disease pathway identified
Posted - in Research Highlights
Mechanism unrelated to microtubule-severing ability
SPG31 studied in fruit flies
Posted - in Research Highlights
Flavonoid treatment restores impaired function
Review of 147 HSP studies of 13,570 HSPers
Posted - in Research Highlights
Revealing big picture overview
New HSP genotypes and phenotypes
Posted - in Research Highlights
Research from Russia, China, Japan, Poland, Italy, Canada, Czech Republic, Spain, the UK and Iran
Search for biomarker of complicated HSP
Posted - in Research Highlights
Retinal nerve fibre thickness studied
Special imaging shows differences due to HSP
Posted - December 2019 in Research Highlights
Potential as a biomarker of progression
Two studies of SPG7
Posted - in Research Highlights
Parkinsonism and a potential eye movement biomarker
SPG2 has a hugely variable presentation
Posted - in Research Highlights
“Neighbour” genes involved in complex, early-onset forms
SPG13 mechanism described
Posted - in Research Highlights
Same gene & mechanism causes another disorder
New HSP genotypes and phenotypes
Posted - in Research Highlights
Research from The Netherlands, Sweden, Russia, USA, Italy, Brazil, UK, Japan, France, Switzerland, Germany, Tunisia, Iran, China, Turkey
Advances in understanding of the HSPs
Posted - September 2019 in Research Highlights
Insight into impaired functions and underlying mechanisms
Three rapid tests of HSP features developed
Posted - in Research Highlights
Potential drug target for SPG4 identified
New explanation for SPG4 causal mechanism
Posted - in Research Highlights
Both too little & too much Spastin to blame
Mitochondrial dynamics and HSP axon defects
Posted - in Research Highlights
Corrected by having less of key protein DRP1
