Research Highlights

Test for potential biomarker established

Posted - September 2020 in Research Highlights

Relevance for HSP clinical trials

New HSP genotypes & phenotypes

Posted - in Research Highlights

Research from China, Japan, Russia, USA, Turkey, Italy, Germany and Taiwan

Reduced axon transport in SPG4 degeneration

Posted - May 2020 in Research Highlights

Consequence of higher sensitivity to oxidative stress

Importance of lipid droplet metabolism in HSP

Posted - in Research Highlights

Fundamental processes and potential drug targets

Mechanism of AP-4 related HSPs clarified

Posted - in Research Highlights

Applies to HSP types 47, 50, 51 and 52

SPG52 found in people with cerebral palsy

Posted - in Research Highlights

Three new mutations identified

2 cases of SPG9 related to pregnancy

Posted - in Research Highlights

Amino acid deficiency found

SPG11 mechanism examined in depth

Posted - in Research Highlights

Initial impact is early in neurodevelopment

New HSP genotypes and phenotypes

Posted - in Research Highlights

Research from Poland, Sudan, Spain, Iran, Korea, China, Czech Republic, Taiwan, Turkey, Mexico and Italy

Earlier HSP onset in successive generations

Posted - February 2020 in Research Highlights

Missense mutations also related to earlier onset

Potential treatment for SPG5 HSP identified

Posted - in Research Highlights

Promising results in mouse studies

New SPG4 disease pathway identified

Posted - in Research Highlights

Mechanism unrelated to microtubule-severing ability

SPG31 studied in fruit flies

Posted - in Research Highlights

Flavonoid treatment restores impaired function

Review of 147 HSP studies of 13,570 HSPers

Posted - in Research Highlights

Revealing big picture overview

New HSP genotypes and phenotypes

Posted - in Research Highlights

Research from Russia, China, Japan, Poland, Italy, Canada, Czech Republic, Spain, the UK and Iran

Search for biomarker of complicated HSP

Posted - in Research Highlights

Retinal nerve fibre thickness studied

Special imaging shows differences due to HSP

Posted - December 2019 in Research Highlights

Potential as a biomarker of progression

New HSP gene PCYT2

Posted - in Research Highlights

Associated with recessive, complicated HSP

Suspected new HSP gene SPTAN1

Posted - in Research Highlights

Huge HSP genetics study in Canada

Two studies of SPG7

Posted - in Research Highlights

Parkinsonism and a potential eye movement biomarker