Research Highlights
SPG30 mechanism clarified
Posted - December 2019 in Research Highlights
Increased, not decreased, activity found
SPG2 has a hugely variable presentation
Posted - in Research Highlights
“Neighbour” genes involved in complex, early-onset forms
SPG13 mechanism described
Posted - in Research Highlights
Same gene & mechanism causes another disorder
New HSP genotypes and phenotypes
Posted - in Research Highlights
Research from The Netherlands, Sweden, Russia, USA, Italy, Brazil, UK, Japan, France, Switzerland, Germany, Tunisia, Iran, China, Turkey
Advances in understanding of the HSPs
Posted - September 2019 in Research Highlights
Insight into impaired functions and underlying mechanisms
Three rapid tests of HSP features developed
Posted - in Research Highlights
Potential drug target for SPG4 identified
New explanation for SPG4 causal mechanism
Posted - in Research Highlights
Both too little & too much Spastin to blame
Mitochondrial dynamics and HSP axon defects
Posted - in Research Highlights
Corrected by having less of key protein DRP1
SPG35 HSP overlaps FAHN & leukodystrophy
Posted - in Research Highlights
Phenotype, disease course, clinical & imaging biomarkers
New, dominant form of HSP, SPG80, described
Posted - in Research Highlights
Found in 10 geographically diverse families worldwide
Atlastin’s role in SPG3A explored
Posted - in Research Highlights
Mechanism and dynamics of impairment described
New HSP genotypes and phenotypes
Posted - in Research Highlights
Research from the UK, China, Pakistan, Italy, Spain, France, Turkey, Austria, Canada, USA & Germany
Large study of SPG7 HSP
Posted - June 2019 in Research Highlights
Genotype-phenotype correlations described
New brain imaging technology delivers
Posted - in Research Highlights
Brain Stem Atlas identifies SPG7 changes
POLR3A gene related syndromes include HSP
Posted - in Research Highlights
Large Norwegian study confirms earlier research
New HSP genotypes and phenotypes
Posted - in Research Highlights
Research from Iran, USA, Italy, Germany, Spain, Bulgaria, Canada, Austria, Saudi Arabia, China, Ireland and Finland
