Research Highlights
Mitochondrial impairment studied in SPG15 & 48 HSP
Posted - June 2018 in Research Highlights
Function restored with treatment in lab experiments
SPG10 HSP gene now linked with Motor Neurone Disease
Posted - in Research Highlights
Previously linked to Charcot Marie Tooth
New HSP gene ACO2 discovered
Posted - in Research Highlights
Associated with recessive complicated HSP
Mechanism of AP-4 related HSPs investigated
Posted - in Research Highlights
AP-4 deficiency underlies four types of HSP
SPAST mutation affects adjacent gene
Posted - in Research Highlights
Combined effect causes complicated HSP
EPT1 mutation causes complicated HSP
Posted - in Research Highlights
Affects myelin sheath that covers nerves
Ataxia-spasticity spectrum disorders
Posted - in Research Highlights
Limitations in classification and diagnosis
New HSP genotypes and phenotypes
Posted - in Research Highlights
Research from France, Canada, Turkey, Germany, Norway, Spain, Italy, South Korea, India and the USA
Biomarker discovery for SPG5 HSP
Posted - February 2018 in Research Highlights
Two cholesterol derivatives identified
DDHD1 and DDHD2 HSP genes investigated
Posted - in Research Highlights
Lipid metabolism dysfunction the common cause
Adaptor Protein (AP) genes linked with 5 types of HSP
Posted - in Research Highlights
Mechanisms & processes described in 3 research studies
Rare form of SPG4 HSP misdiagnosed
Posted - in Research Highlights
Early-onset symptoms “misleading”
New HSP mutation found in FA2H gene
Posted - in Research Highlights
Early-onset and rapid progression SPG35 HSP
Promising treatment found for SPG5 HSP
Posted - December 2017 in Research Highlights
Atorvastatin reduces toxic fatty compounds in the brain
Next Generation gene testing telling a story
Posted - in Research Highlights
Much of HSP genetics still not understood
HSP differences in identical twins
Posted - in Research Highlights
More than genetic inheritance at play
Brain activity levels potential diagnostic for SPG4 HSP
Posted - in Research Highlights
Differences with disease severity identified
SPG2 HSP mechanism described
Posted - in Research Highlights
Loss of specialised support cells the cause
