Amino acid deficiency found
Research Highlights
SPG11 mechanism examined in depth
Initial impact is early in neurodevelopment
New HSP genotypes and phenotypes
Research from Poland, Sudan, Spain, Iran, Korea, China, Czech Republic, Taiwan, Turkey, Mexico and Italy
Earlier HSP onset in successive generations
Missense mutations also related to earlier onset
Potential treatment for SPG5 HSP identified
Promising results in mouse studies
New SPG4 disease pathway identified
Mechanism unrelated to microtubule-severing ability
SPG31 studied in fruit flies
Flavonoid treatment restores impaired function
Review of 147 HSP studies of 13,570 HSPers
Revealing big picture overview
New HSP genotypes and phenotypes
Research from Russia, China, Japan, Poland, Italy, Canada, Czech Republic, Spain, the UK and Iran
Search for biomarker of complicated HSP
Retinal nerve fibre thickness studied