Research Highlights
New HSP mutation found in FA2H gene
Posted - February 2018 in Research Highlights
Early-onset and rapid progression SPG35 HSP
Promising treatment found for SPG5 HSP
Posted - December 2017 in Research Highlights
Atorvastatin reduces toxic fatty compounds in the brain
Next Generation gene testing telling a story
Posted - in Research Highlights
Much of HSP genetics still not understood
HSP differences in identical twins
Posted - in Research Highlights
More than genetic inheritance at play
Brain activity levels potential diagnostic for SPG4 HSP
Posted - in Research Highlights
Differences with disease severity identified
SPG2 HSP mechanism described
Posted - in Research Highlights
Loss of specialised support cells the cause
New HSP genotypes and phenotypes
Posted - in Research Highlights
From China, Japan, Italy, Brazil, UK, Korea, USA, Israel, Iran, Moldova, Greece, France, Belgium, Germany, UAE, Russia
Lower motor neurons impaired in some HSPs
Posted - in Research Highlights
Classification based on motor neuron involvement
Hereditary Ataxias and Spastic Paraplegias
Posted - in Research Highlights
Genes and symptoms overlap
HSP classification and terminology
Posted - in Research Highlights
Genetics explosion prompts update
New HSP genotypes and phenotypes
Posted - in Research Highlights
From Canada, USA, Pakistan, France, Japan, Czech Republic and Belgium
Questioning disease classification systems
Posted - June 2017 in Research Highlights
A mechanistically inspired classification proposed
Particular form of Spastin is toxic
Posted - in Research Highlights
Interferes with fast axonal transport
Axonal degeneration in HSP
Posted - in Research Highlights
Link between different classes of HSP proteins
SPG11 mutations observed in HSP, ALS and CMT
Posted - in Research Highlights
Common mechanism of lipid accumulation in lysosomes
Impairment of Atlastin protein causes SPG3A type HSP
Posted - in Research Highlights
Important role in the regeneration of neurons disrupted
So-called Junk DNA not really junk
Posted - in Research Highlights
Junk DNA mutations found to cause HSP
More than 60 mutations exist for SPG3A HSP
Posted - in Research Highlights
Can’t predict symptom profile in this HSP type
