Research Highlights
New HSP genotypes and phenotypes
Posted - December 2017 in Research Highlights
From China, Japan, Italy, Brazil, UK, Korea, USA, Israel, Iran, Moldova, Greece, France, Belgium, Germany, UAE, Russia
Lower motor neurons impaired in some HSPs
Posted - in Research Highlights
Classification based on motor neuron involvement
Hereditary Ataxias and Spastic Paraplegias
Posted - in Research Highlights
Genes and symptoms overlap
HSP classification and terminology
Posted - in Research Highlights
Genetics explosion prompts update
New HSP genotypes and phenotypes
Posted - in Research Highlights
From Canada, USA, Pakistan, France, Japan, Czech Republic and Belgium
Questioning disease classification systems
Posted - June 2017 in Research Highlights
A mechanistically inspired classification proposed
Particular form of Spastin is toxic
Posted - in Research Highlights
Interferes with fast axonal transport
Axonal degeneration in HSP
Posted - in Research Highlights
Link between different classes of HSP proteins
SPG11 mutations observed in HSP, ALS and CMT
Posted - in Research Highlights
Common mechanism of lipid accumulation in lysosomes
Impairment of Atlastin protein causes SPG3A type HSP
Posted - in Research Highlights
Important role in the regeneration of neurons disrupted
So-called Junk DNA not really junk
Posted - in Research Highlights
Junk DNA mutations found to cause HSP
More than 60 mutations exist for SPG3A HSP
Posted - in Research Highlights
Can’t predict symptom profile in this HSP type
New HSP genetic findings
Posted - in Research Highlights
From Mali, Norway, Germany, Qatar, Italy, Turkey, Saudi Arabia, Pakistan, USA, Poland
Mitochondrial dysfunction in SPG31 HSP
Posted - February 2017 in Research Highlights
Function restored in cell samples
Two siblings with blood disorder and HSP
Posted - in Research Highlights
Both conditions autosomal recessive inheritance
Large national HSP database in Canada
Posted - in Research Highlights
Valuable resource for much-needed research
SPG42 HSP mechanism now well understood
Posted - in Research Highlights
Study of mice confirms earlier findings
Complicated form of HSP linked to new gene
Posted - in Research Highlights
Impaired lipid metabolism mechanism
SPG78 HSP mechanism investigated
Posted - in Research Highlights
Pathway leads to sell organelle impairment
