Insight into how SPG80 is caused
Research Highlights
New HSP genotypes and phenotypes
Research from USA, Germany, Turkey, China, India, France, Japan, Austria
Huge study of SPG4 in Italy
Important data and findings generated
How SPG4 first shows up
Potential biomarker for treatment response
Another potential mechanism in SPG4
Toxic effect rather than shortage in some cases
New HSP mouse for testing potential therapies
Mouse exhibits a range of HSP characteristics
Disease-causing mechanism of SPG15 explored
Links between lysosomes, lipids & nerve function
A new explanation for AP-4 deficiency syndrome
Reduced levels of a key enzyme affect neurite growth
Lipid imbalance in SPG61 described
Potential therapeutic pathway identified
Role of Spastin & cognitive dysfunction in HSP
Understanding of AMPAR receptor advanced