Research Highlights

New gene interacts with Spastin

Posted - March 2012 in Research Highlights

Implicated in cell structural abnormalities

HSP and its ‘cousin’ CMT

Posted - in Research Highlights

Comparing genetics and cell function

Assessing nerve abnormalities in HSP

Posted - in Research Highlights

New measurement method tested

Large study of SPG31

Posted - in Research Highlights

Both pure & complex HSP found

Questions raised about Botox

Posted - December 2011 in Research Highlights

muscle loss and weakness with long term use

Large HSP survey in Japan

Posted - in Research Highlights

321 HSPers from 144 families registered

New HSP gene testing method

Posted - in Research Highlights

Sporadic HSP cases analysed

Link between reflexes and spasticity questioned

Posted - in Research Highlights

Over-active reflexes and calf muscle spasticity

KIF5 study relevant to SPG10 HSP

Posted - in Research Highlights

Neuronal transport mechanism identified

Dementia in some SPG4 HSPers

Posted - September 2011 in Research Highlights

Linked with Alzheimer’s gene

Rare HSP linked to Huntington’s disease

Posted - in Research Highlights

Both detected in one family over generations

Epilepsy and HSP

Posted - in Research Highlights

SPG6 risk identified

Link between HSP & Charcot-Marie-Tooth disease

Posted - in Research Highlights

SPG10 and CMT2 may be from same gene mutation

SPG18 complicated HSP described

Posted - in Research Highlights

List of affected cellular functions expanding

SPG4 mutations studied

Posted - in Research Highlights

Process for regulating Spastin levels defined

Stem cell research progress report, May 2011

Posted - June 2011 in Research Highlights

Research project on target

Gender analysis of SPG4 HSP

Posted - in Research Highlights

Significantly more males than females

Atlastin function in cells explored

Posted - in Research Highlights

Important for cell membrane fusion

In-depth study of SPG31 HSP

Posted - in Research Highlights

Both pure and complicated forms found

Gene testing technologies

Posted - in Research Highlights

Limitations and workarounds